By Gerardo R. Vasta PhD, Hafiz Ahmed PhD
Introduces Groundbreaking ways for Assessing Lectin Function
Lectins and their ligands are lower than really a heavy microscope because of their strength functions to pharmacology, immunology, melanoma remedy, and agriculture. With turning out to be curiosity within the glycobiology box, the physique of analysis relating to lectin roles has grown at an explosive expense, really some time past twenty years. Animal Lectins: A useful View provides the main updated research of those carbohydrate-binding, and in all probability lifesaving, proteins in a single finished quantity.
This standard-setting source provides new insights into the organic roles of so much animal lectins, together with their functionality in an infection prevention via innate immunity. It additionally discusses such lectin behaviors as:
- Glycoprotein folding
- Sorting and targeting
- Cell adhesion
- Cell-cell interactions and signaling
Describes the Structural foundation of Protein-Carbohydrate Interactions
Under the editorial counsel of 2 top protein chemistry specialists and with contributions from well-recognized box gurus, this booklet logically and systematically discusses either intracellular and extracellular lectin capabilities. it's a necessary springboard for destiny box study and a transparent and concise wisdom base that glycobiology, biochemistry, and immunology researchers can't have the funds for to be without.
Read or Download Animal Lectins: A Functional View PDF
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Additional resources for Animal Lectins: A Functional View
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Furthermore, some unique structural features can be identified in the most divergent family members. , 1999). , 1999). , 2004). , 1998; Saussez and Kiss, 2006). 2) of galectin-7 shows that dimerization of this lectin is very different from those of dimeric galectins. , 1998; Rini and Lobsanov, 1999). 3 CARBOHYDRATE-BINDING SPECIFICITY OF GALECTINS THEIR CARBOHYDRATE-BINDING SITES AND The ability of galectins to discriminate among carbohydrate structures is striking. , 1990, 1996, 2004). For most galectins, LacNAc and thiodigalactoside (TDG) are 5–10 times more active than Lac.
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